British Air Force Typhoon FGR4s have operated alongside French warplanes in a coordinated attack targeting an hidden munitions depot in Syrian territory used by the IS group, according to the UK Ministry of Defence.
The location, located using intelligence, was assessed as storing arms and explosives, the announcement noted, and was positioned in mountains just to the north of Palmyra in central Syria.
"The RAF jets employed laser-guided Paveway IV weapons to hit a several access tunnels providing entry to the facility... preliminary assessments are that the strike was effective," the MoD said.
There was no sign of any harm to civilians in the attack late on Saturday and every plane involved returned safely, the MoD added.
The Typhoon fighters were backed up by a Voyager refuelling tanker.
Daesh - referred to as ISIS - imposed jihadist rule over large swathes of both Syria and Iraq until 2019.
"This strike shows the UK's leading role, and resolve to work closely with allied nations, to eradicate any resurgence of Daesh and their harmful and extremist ideologies in the Middle East," UK Defence Secretary John Healey remarked.
UK warplanes have performed surveillance missions over Syria to "forestall any attempted comeback" of IS following its defeat at the climactic battle in Baghuz in the year 2019, the ministry said.
"I must thank every member of our armed forces who took part in this strike for their professionalism and their valour," Healey added. "They were among numerous British personnel deployed over Christmas and New Year. This operation, to remove terrorist threats who endanger our way of life, demonstrates how our armed forces are always on standby, continuously, ensuring Britain's security within its borders and influential overseas."
In December, the US military conducted what it termed a "massive strike" against IS targets in the country, subsequent to an ambush killed two US servicemembers and a civilian interpreter in Palmyra.
The United Nations reports IS still boasts roughly 5-7 thousand fighters in Syria and Iraq.
